Author

Mahati Rayadurgam

La Jolla Institute for ImmunologyORCID 0009-0009-5206-6312Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alicia GibbonsiD· 3 shared Maija CoreyiD· 3 shared Priyanka SaminathaniD· 3 shared Sonia SharmaiD· 3 shared Camille FangiD· 2 shared Carolina Altbaum· 2 shared Mousa VatanmakanianiD· 2 shared Namratha NadigiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Alicia GibbonsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologyFrontiers in ImmunologyPeer-reviewedJul 31, 2026

LPC 18:2-Driven Apoptosis In Neutrophils Is Non-Inflammatory and Lipid Raft Dependent

Priyanka Saminathan, Alicia Gibbons, Ian T. Mathews…·Sonia Sharma

This study compares the effects of LPC 18:2 and LPC 16:0 on neutrophil apoptosis, showing LPC 18:2 induces non-inflammatory, lipid raft-dependent apoptosis while LPC 16:0 causes inflammatory pyroptosis.

DOI 10.3389/fimmu.2026.1807766

humanbulk RNA-seq

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ImmunologyThe Journal of ImmunologyPeer-reviewedJul 15, 2026

Deoxyguanosine Kinase Deficiency Couples Purine Metabolism to Innate Immune Activation and Lipid Accumulation in Hepatocytes

Maija Corey, Mahati Rayadurgam, Mousa Vatanmakanian…·Sonia Sharma

This study shows DGUOK deficiency disrupts purine metabolism, leading to lipid accumulation and innate immune activation in hepatocytes, independent of mtDNA depletion.

1 citation

humanbulk RNA-seq

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NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewedJan 2, 2026

Unmasking Early Microglial Remodeling in an Alzheimer's Disease Mouse Model

Priyanka Saminathan, Sara McArdle, Maija Corey…·Sonia Sharma

The paper quantifies early microglial structural changes in 5xFAD mice before amyloid plaques, revealing sex-specific differences and a link between morphology and phagolysosomal activity.

3 citationstop 4%

mousespatial transcriptomics

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