Author

Hugues Duffau

Centre National de la Recherche ScientifiqueORCID 0000-0002-6558-2342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chantal Ripoll· 2 shared Christine GranotieriD· 2 shared Donovan PineauiD· 2 shared François Dominique BoussiniD· 2 shared Jean‐Philippe HugnotiD· 2 shared Kasandra Aguilar CázareziD· 2 shared Laurent GauthieriD· 2 shared Lei ZhangiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Chantal Ripoll

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyActa Neuropathologica CommunicationsPeer-reviewedJul 20, 2026

Multi-omics characterization of IDH-mutant astrocytoma-derived cell lines reveals NOTCH-regulated plastic quiescent astrocyte-like state

Leonor Garcia, Christine Granotier, Donovan Pineau…·Jean‐Philippe Hugnot

The paper establishes and characterizes IDH-mutant astrocytoma cell lines, revealing NOTCH-regulated plasticity between astrocyte-like and oligodendrocyte-like states.

DOI 10.1186/s40478-026-02316-9

humanscRNA-seq

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Cancer BiologyMolecular OncologyPeer-reviewedApr 23, 2026

Endothelin Signaling via EDNRB receptor Reduces Proliferation and Promotes Proneural-to-Mesenchymal Transition in Gliomas

Donovan Pineau, Leonor Garcia, Hugo Arnold…·Jean‐Philippe Hugnot

This study identifies endothelin signaling via EDNRB as a regulator of glioma cell proliferation and proneural-to-mesenchymal transition, with distinct receptor expression and functional roles in different tumor subtypes.

1 citation

humanproteomics

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