Author

Laurent Gauthier

InsermORCID 0000-0003-4644-7660Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Laurent Gauthier1 paper · Innate Pharma (France)

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Christine GranotieriD· 3 shared François Dominique BoussiniD· 3 shared Chantal Ripoll· 2 shared Donovan PineauiD· 2 shared Hugues DuffauiD· 2 shared Jean‐Philippe HugnotiD· 2 shared Kasandra Aguilar CázareziD· 2 shared Lei ZhangiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Christine GranotierORCID

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3 papers

Recent·Most cited

Cancer BiologyActa Neuropathologica CommunicationsPeer-reviewedJul 20, 2026

Multi-omics characterization of IDH-mutant astrocytoma-derived cell lines reveals NOTCH-regulated plastic quiescent astrocyte-like state

Leonor Garcia, Christine Granotier, Donovan Pineau…·Jean‐Philippe Hugnot

The paper establishes and characterizes IDH-mutant astrocytoma cell lines, revealing NOTCH-regulated plasticity between astrocyte-like and oligodendrocyte-like states.

DOI 10.1186/s40478-026-02316-9

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Cancer BiologyCell Reports MethodsPeer-reviewedMay 5, 2026

Advanced human cerebral organoids as a model for investigating glioma stem cell interactions with microglia and vascular cells and response to radiotherapy

Jérémy Raguin, Noa Legrand, Thierry Kortulewski…·Marc‐André Mouthon

This paper develops a vascularized cerebral organoid model with microglia to study glioma stem cell interactions and radiotherapy response.

4 citationstop 1%

humanorganoid / primary culture

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Cancer BiologyMolecular OncologyPeer-reviewedApr 23, 2026

Endothelin Signaling via EDNRB receptor Reduces Proliferation and Promotes Proneural-to-Mesenchymal Transition in Gliomas

Donovan Pineau, Leonor Garcia, Hugo Arnold…·Jean‐Philippe Hugnot

This study identifies endothelin signaling via EDNRB as a regulator of glioma cell proliferation and proneural-to-mesenchymal transition, with distinct receptor expression and functional roles in different tumor subtypes.

1 citation

humanproteomics

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