Author

Allister J. Loughran

St. Jude Children's Research HospitalORCID 0000-0002-6564-5526Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bárbara dos Santos PassaiaiD· 1 shared Bensheng JuiD· 1 shared Beth ManniD· 1 shared Brian J. AbrahamiD· 1 shared Burgess B. FreemaniD· 1 shared Ching‐Heng ChouiD· 1 shared Cliff S. GuyiD· 1 shared Daniel DarnelliD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Bárbara dos Santos PassaiaORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedFeb 28, 2025

Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid.

Min Pan, Yinwen Zhang, William C. Wright…·Paul Geeleher

The paper investigates RA's limited effect on primary neuroblastoma tumors but efficacy in clearing bone marrow cells, identifying BMP signaling as a key determinant of cell fate and RA sensitivity.

7 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 19, 2021

Fetal neural progenitors process TLR signals from bacterial components to enhance proliferation and rework brain development

Beth Mann, Jeremy Chase Crawford, Kavya Reddy…·ELAINE I. TUOMANEN

The paper shows bacterial PAMPs activate TLR2/6 on fetal NPCs, enhancing proliferation and altering brain development in mice.

DOI 10.1101/2021.10.19.464985

mousebulk RNA-seq

𝕏 PostBluesky