Author
University of California, San FranciscoORCID 0000-0002-6600-7032Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jongbin Kim, G.J. Correy, Brendan W. Hall…·James S. Fraser
On 489 evaluable new Mac1 complexes, AlphaFold3, Chai-1 and Boltz-2 placed over half of ligands within 2 Å, but on docking hit-lists AF3 and Boltz-2 added little over docking.
Rahul K. Suryawanshi, Priyadarshini Jaishankar, G. J. Correy…·James S. Fraser
This study identifies Mac1 as a therapeutic target for SARS-CoV-2 and demonstrates that AVI-4206, a small molecule inhibitor, reduces viral replication and improves survival in an animal model.
Matthew T. Klope, Poulami Talukder, Brian R. Blank…·Adam R. Renslo
The paper describes the discovery of new antimalarial trioxolanes effective against artemisinin-resistant parasites and their potential as development candidates for malaria treatment.