Author

Michael R. Setzer

Henry M. Jackson FoundationORCID 0000-0002-6652-5446Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 3

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 3 Organism:human· 3 Approach:statistical model· 3 Approach:Bayesian inference· 2 Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Christopher T. RentschiD· 3 shared Henry R. KranzleriD· 3 shared Joshua C. GrayiD· 3 shared Christal N. DavisiD· 2 shared Mingjian ShiiD· 2 shared Samantha G. MaloneiD· 2 shared Tommy GunawaniD· 2 shared Zachary Piserchia· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Christopher T. RentschORCID

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3 papers

Recent·Most cited

Shared Genetic Architecture and Neurobiological Pathways of Problematic Alcohol Use and Anxiety Disorders

Mingjian Shi, Tommy Gunawan, Samantha G. Malone, Michael R. Setzer, Zachary Piserchia, Christal N. Davis, Christopher T. Rentsch, Eleni Friligkou, Hang Zhou, Renato A Polimanti, Lu Wang, Nataraja Sarma Vaitinadin, Henry R. Kranzler, Joshua C. Gray

This study identifies shared genetic and neurobiological pathways between problematic alcohol use and anxiety disorders using genomic analyses.

Neuropsychopharmacology · Jul 13, 2026Peer-reviewedGenetic & Genomic Medicine

Genetic and Proteomic Investigation of the Smoking-Parkinson Disease Association

Mingjian Shi, Tommy Gunawan, Michael R. Setzer, Najeah Okashah, Yue Liu, Thomas S. Wingo, Aliza P. Wingo, Daniel Weintraub, Michael A. Schwarzschild, Christopher T. Rentsch, Henry R. Kranzler, Joshua C. Gray

This study investigates the causal relationship between smoking and Parkinson's disease using genetic and proteomic data, identifying shared biological pathways and potential therapeutic targets.

medRxiv · Apr 20, 2026 · PreprintGenetic & Genomic Medicine

Alcohol use disorder and body mass index show genetic pleiotropy and shared neural associations

Samantha G. Malone, Christal N. Davis, Zachary Piserchia, Michael R. Setzer, Sylvanus Toikumo, Hang Zhou, Emma L. Winterlind, Joel E. Gelernter, Amy C. Justice, Lorenzo Leggio, Christopher T. Rentsch, Henry R. Kranzler, Joshua C. Gray

The paper investigates genetic and neural overlaps between alcohol use disorder and BMI, finding polygenic overlap despite minimal genetic correlation and identifying shared brain regions involved in executive function and reward.

Nature Human Behaviour · Mar 31, 2025Peer-reviewedGenetic & Genomic Medicine