Author

Yue Liu

Nagoya University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetic & Genomic Medicine· 2 Pharmacology & Toxicology· 2 Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Aliza P. WingoiD· 2 shared Thomas S. WingoiD· 2 shared Akihiro MouriiD· 1 shared Anantharaman ShantaramaniD· 1 shared Anbupalam ThalamuthuiD· 1 shared Andrii KopachiD· 1 shared Anne PoljakiD· 1 shared Arnab Mandal· 1 shared

Activity by Year

2020-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Aliza P. WingoORCID

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Author profile →

6 papers

Recent·Most cited

A Designed Ankyrin Repeat Protein (DARPin) Targeting EGFR Inhibits Ovulation and Enables a Novel Platform for Studying Ovarian Biology and Pathophysiology

Yubing Liu, Jiyang Zhang, Shichao Liu, Connie Mitra, Yue Liu, Hannah M. VanBenschoten, Brittany A. Goods, Feng Chen, Shuo Xiao

An engineered EGFR-targeting DARPin selectively inhibits ovulation through extracellular receptor blockade and establishes a versatile platform for investigating ovarian signaling and reproductive disorders.

bioRxiv · Jun 26, 2026 · PreprintPharmacology & Toxicology

Genetic and Proteomic Investigation of the Smoking-Parkinson Disease Association

Mingjian Shi, Tommy Gunawan, Michael R. Setzer, Najeah Okashah, Yue Liu, Thomas S. Wingo, Aliza P. Wingo, Daniel Weintraub, Michael A. Schwarzschild, Christopher T. Rentsch, Henry R. Kranzler, Joshua C. Gray

This study investigates the causal relationship between smoking and Parkinson's disease using genetic and proteomic data, identifying shared biological pathways and potential therapeutic targets.

medRxiv · Apr 20, 2026 · PreprintGenetic & Genomic Medicine

Antipsychotic-like effects of the selective Rho-kinase 2 inhibitor KD025 in genetic and pharmacological mouse models of schizophrenia

Rinako Tanaka, Jingzhu Liao, Yue Liu, Wenjun Zhu, Kisa Fukuzawa, Masamichi Kondo, Masahito Sawahata, Daisuke Mori, Akihiro Mouri, Hisayoshi Kubota, Daiki Tachibana, Yohei Kobayashi, Tetsuo Matsuzaki, Taku Nagai, Toshitaka Nabeshima, , Kiyofumi Yamada

This study shows that the selective ROCK2 inhibitor KD025 has antipsychotic-like effects and fewer side effects in schizophrenia models.

Molecular Psychiatry · Apr 1, 2026Peer-reviewedPharmacology & Toxicology

Neurodegeneration risk variants promote lysosomal TMEM106B fibrilaccumulation

John Michael Replogle, Jordan D. Marks, Martin G. Fernandez, Hebao Yuan, Dahyun Yu, Elizabeth Winters, Vidhya Maheswari Jawahar, Rishi Deshmukh, Renaldo Sutanto, Isabelle Kowal, Ashley M. Frankenfield, Rachel Shi, Yari Carlomagno, Karen R. Jansen‐West, Tiffany W. Todd, , Michael Emmerson Ward

The paper identifies TMEM106B fibril accumulation as a shared mechanism in neurodegeneration linked to genetic variants in TMEM106B and GRN.

bioRxiv · Mar 28, 2026 · PreprintCell Biology

The contribution of Apoliproprotein E genetic variation to dementia risk in British South Asians

Benjamin M. Jacobs, Avinash Chandra, Isabelle Francesca Foote, Faiza Gul Durrani, Sheena Waters, Yue Liu, Petroula Proitsi, Cara L. Croft, Dylan M. Williams, Sarah Finer, Stuart Christopher Gorthorn Rison, Arnab Mandal, Moneeza Kalhan Siddiqui, David A. van Heel, Charles R. Marshall

This study assesses the association between APOE genetic variants and dementia risk in British South Asians using healthcare records and genotyping data.

Apollo (University of Cambridge) · Jan 1, 2026Peer-reviewedGenetic & Genomic Medicine

Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins

Matthew Wai Kin Wong, Anbupalam Thalamuthu, Nady Braidy, Karen A. Mather, Yue Liu, Liliana G Ciobanu, Bernhardt T. Baune, Nicola J. Armstrong, John B. Kwok, Peter R. Schofield, Margaret J. Wright, David J. Ames, Russell Pickford, Teresa Lee, Anne Poljak, Perminder Singh Sachdev

This study examines the heritability and environmental influences on the plasma lipidome in older Australian twins, finding most variation is due to unique environmental factors.

eLife · Jul 22, 2020Peer-reviewedGenetics