Author

Christina R. Hartigan

Broad InstituteORCID 0000-0002-6668-2222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Steven A. CarriD· 2 shared Alexander GabeliD· 1 shared Alexandra R. CoccoiD· 1 shared Andrew G. ReidenbachiD· 1 shared Eric Vallabh MinikeliD· 1 shared Eric W. KuhniD· 1 shared Franc LlorensiD· 1 shared Gregory J. Raymond· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Steven A. CarrORCID

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2 papers

Recent·Most cited

SHIFTR enables the unbiased and multiplexed identification of proteins bound to specific RNA regions in live cells

Jens Aydin, Alexander Gabel, Sebastian Zielinski, Sabina Ganskih, Nora Schmidt, Christina R. Hartigan, Monica Schenone, Steven A. Carr, Mathias Munschauer

SHIFTR identifies proteins bound to specific RNA regions in live cells with high accuracy and low input, enabling comprehensive RNA interactome mapping.

Nucleic Acids Research · Jan 10, 2024Peer-reviewedMolecular Biology

Domain-specific quantification of prion protein in cerebrospinal fluid by targeted mass spectrometry

Eric Vallabh Minikel, Eric W. Kuhn, Alexandra R. Cocco, Sonia M. Vallabh, Christina R. Hartigan, Andrew G. Reidenbach, Jiri Safar, Gregory J. Raymond, Michael D. McCarthy, Rhonda O’Keefe, Franc Llorens, Inga Zerr, Sabina Capellari, Piero Parchi, Stuart L. Schreiber, Steven A. Carr

The paper develops a targeted mass spectrometry method to quantify prion protein in CSF, confirming that reduced PrP levels in prion disease are due to the disease process, not ELISA artifacts.

Molecular & Cellular Proteomics · Sep 26, 2019Peer-reviewedNeuroscience