Author

Debora Alejandra Ledesma

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-6670-7645Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander J. LazariD· 1 shared Allie H. GrossmanniD· 1 shared Aron Y. JooniD· 1 shared Barbara G. Knighton· 1 shared Christian Y. Beke Onana· 1 shared Courtney W. HudgensiD· 1 shared David A. KircheriD· 1 shared Grant M. FischeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander J. LazarORCID

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1 paper

Recent·Most cited

Oxidative Phosphorylation (OXPHOS) Promotes the Formation and Growth of Melanoma Lung and Brain Metastases

Renato A. Guerrieri, Grant M. Fischer, David A. Kircher, Aron Y. Joon, Josué Cortez, Allie H. Grossmann, Courtney W. Hudgens, Debora Alejandra Ledesma, Rossana Lazcano, Christian Y. Beke Onana, Barbara G. Knighton, Swaminathan Kumar, Qianghua Hu, Y. N. Vashisht Gopal, Jennifer Leigh McQuade, , Michael A. Davies

This study shows that oxidative phosphorylation (OXPHOS) is critical for melanoma metastasis to the lungs and brain, based on analysis of human patients and mouse models.

bioRxiv · Jan 23, 2025 · PreprintCancer Biology