Author

Grant M. Fischer

Brigham and Women's HospitalORCID 0000-0003-3730-9004Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander J. LazariD· 1 shared Allie H. GrossmanniD· 1 shared Anna MandinovaiD· 1 shared Arianna ZhangiD· 1 shared Aron Y. JooniD· 1 shared Barbara G. Knighton· 1 shared Christian Y. Beke Onana· 1 shared Christine Guo LianiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alexander J. LazarORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 23, 2025

Oxidative Phosphorylation (OXPHOS) Promotes the Formation and Growth of Melanoma Lung and Brain Metastases

Renato A. Guerrieri, Grant M. Fischer, David A. Kircher…·Michael A. Davies

This study shows that oxidative phosphorylation (OXPHOS) is critical for melanoma metastasis to the lungs and brain, based on analysis of human patients and mouse models.

3 citations

mousehuman

𝕏 PostBluesky

Cancer BiologyLaboratory InvestigationPeer-reviewedJul 26, 2024

PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation

Rui Fang, Tuulia Vallius, Arianna Zhang…·Christine Guo Lian

This study shows PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation, with reduced 5hmC levels correlating with PRAME upregulation.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky