Molecular BiologyThe FASEB JournalPeer-reviewed
CRISPR/Cas9-mediated genome editing of Schistosoma mansoni acetylcholinesterase
Hong You, Johannes U. Mayer, Rebecca L. Johnston…·Donald Peter McManus
This paper uses CRISPR/Cas9 to edit the acetylcholinesterase gene in Schistosoma mansoni eggs, resulting in reduced AChE activity and decreased granuloma size in mice.
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