Max Friesen

The paper develops a protocol to model insulin sensitivity and resistance in multiple hPSC-derived cell types, showing insulin resistance across various cell types under diabetic conditions.

The paper shows healthy adipocytes protect neighboring cells from viral infection through STING-dependent interferon-alpha secretion, and metabolic dysfunction reduces this antiviral activity.

The paper detects SARS-CoV-2 retrotransposition into host genomes via LINE1 in infected cells but not in transfected cells, using WGS and TagMap methods.