Author

Ryo Kurosawa

Kyoto UniversityORCID 0000-0002-6710-9989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Kei IidaiD· 2 shared Masahiko AjiroiD· 2 shared Masatoshi HagiwaraiD· 2 shared Atsushi TakahashiiD· 1 shared BioBank Japan Project· 1 shared Chikashi C. TeraoiD· 1 shared Hiroki YoshidaiD· 1 shared Hiroshi AkazawaiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Kei IidaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PDIVAS: Pathogenicity predictor for Deep-Intronic Variants causing Aberrant Splicing

Ryo Kurosawa, Kei Iida, Masahiko Ajiro, Tomonari Awaya, Mamiko Yamada, Kenjiro Kosaki, Masatoshi Hagiwara

PDIVAS identifies pathogenic deep-intronic variants causing aberrant splicing with high sensitivity using an ensemble machine-learning model.

BMC Genomics · Oct 10, 2023Peer-reviewedGenetic & Genomic Medicine

Trans-ancestry genome-wide analysis of atrial fibrillation provides new insights into disease biology and enables polygenic prediction of cardioembolic risk

Kazuo Miyazawa, Kaoru Ito, Zhaonan Zou, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Seitaro Nomura, Masato Akiyama, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, BioBank Japan Project, Atsushi Takahashi, Koichi Matsuda, , Issei Komuro

This paper identifies new genetic loci for atrial fibrillation through a trans-ancestry meta-analysis and develops a polygenic risk score linked to cardioembolic risk.

medRxiv · Sep 6, 2021 · PreprintGenetic & Genomic Medicine

Switching of OAS1 splicing isoforms mitigates SARS-CoV-2 infection

Kei Iida, Masahiko Ajiro, Yukiko Muramoto, Toru Takenaga, Masatsugu Denawa, Ryo Kurosawa, Takeshi Noda, Masatoshi Hagiwara

The paper identifies a splicing modifier that switches OAS1 isoforms, enhancing resistance to SARS-CoV-2 infection in human lung cells.

bioRxiv · Aug 23, 2021 · PreprintGenomics