Krishnamurthy Natarajan

This study shows that modulating autophagy with rapamycin improves survival and reduces intestinal injury after radiation, while chloroquine worsens it.

The paper identifies how histone fold domains in TAF12 paralogs mediate their specific association with TFIID and SAGA complexes in Candida albicans.

The paper investigates the modular organization of the SAGA complex in Candida albicans and identifies its role in stress adaptation, morphogenesis, and histone acetylation.

The paper shows that SAGA complex's histone acetylation is essential for filamentation in C. albicans, while NuA4's role is less critical.

The paper identifies TFIID and SAGA complex subunits in C. albicans and shows that TAF12 paralogs form heterodimers through cotranslational assembly, ensuring specificity and stability of histone-like complexes.