In vivo structural characterization of the whole SARS-CoV-2 RNA genome identifies host cell target proteins vulnerable to re-purposed drugs
Lei Sun, Pan Li, Xiaohui Ju, Jian Rao, Wenze Huang, Shaojun Zhang, Tuanlin Xiong, Kui Xu, Xiaolin Zhou, Lili Ren, Qiang Ding, Jianwei Wang, Qiangfeng Cliff Zhang
The paper maps the in vivo structure of SARS-CoV-2 RNA, identifies novel structural features, and predicts host proteins interacting with the RNA using deep learning.
Cell · Apr 1, 2021Peer-reviewedMicrobiology