Author

Leon E. Hugo

QIMR Berghofer Medical Research InstituteORCID 0000-0002-6767-9850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1

Frequent Co-Authors

Alyson AsheiD· 1 shared Alyssa J. PetersoniD· 1 shared Audrey E LenhartiD· 1 shared Constantianus J. M. KoenraadtiD· 1 shared Gorben P. PijlmaniD· 1 shared Gordana RašićiD· 1 shared Gregor J. DevineiD· 1 shared Hans M. SmidiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

Alyson AsheORCID

Author profile →

3 papers

Recent·Most cited

Sequence Homology and Tissue Tropism Determine Superinfection Exclusion of Zika virus in Aedes aegypti Mediated by an insect-specific Binjari-Zika Virus Chimera

Wessel Willemsen, Alyssa J. Peterson, Marleen H. C. Abma-Henkens, Hans M. Smid, Hayden J. Rohlf, Tessa M. Visser, Constantianus J. M. Koenraadt, Roy A. Hall, Monique M. van Oers, Jody Hobson‐Peters, Gorben P. Pijlman, Jessica J. Harrison, Leon E. Hugo, Jelke Jan Fros

bioRxiv · Aug 4, 2026 · PreprintMicrobiology

Conserved but mechanistically diverse piRNA defence against gypsy LTR retrotransposons in insect ovaries

Shashank Chary, Patricia Eugenia Carreira, Sarah Nicholas, Kathryn B. McNamara, Ian Andrew Cockburn, Karin Nordström, Therésa M. Jones, Rosalyn Gloag, Alyson Ashe, Leon E. Hugo, Rippei Hayashi

The paper shows that piRNA pathways in insect ovaries defend against gypsy retrotransposons, with lineage-specific mechanisms across species.

EMBO Reports · Apr 2, 2026Peer-reviewedEvolutionary Biology

Fitness compatibility and dengue virus inhibition in a Bangladeshi strain of Aedes aegypti infected with the Wolbachia strain wAlbB

Hasan Mohammad Al‐Amin, Narayan Gyawali, Melissa C. Graham, Mohammad Shafiul Alam, Audrey E Lenhart, Zhiyong Xi, Gordana Rašić, Nigel W. Beebe, Leon E. Hugo, Gregor J. Devine

The paper creates and characterizes a Wolbachia-infected Aedes aegypti strain with a Dhaka genetic background, showing it has reduced dengue virus transmission potential and comparable fitness to wild-type mosquitoes.

Scientific Reports · Apr 18, 2025Peer-reviewedZoology