Author

Yi Di

Yale UniversityORCID 0000-0002-6768-7076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Organism:human· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Yansheng LiuiD· 4 shared Barbora ŠalovskáiD· 3 shared Chongde WuiD· 2 shared Erli Gao· 2 shared Benjamin E. TurkiD· 1 shared Cassandra Santaella BishopiD· 1 shared George RosenbergeriD· 1 shared Mandar Deepak MuzumdariD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersSystems Biology

Yansheng LiuORCID

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4 papers

Recent·Most cited

Baseline cellular state dictates the molecular impact of KRAS mutant variants in pancreatic cancer cells

Yanixa Quiñones-Avilés, Barbora Šalovská, Cassandra Santaella Bishop, Yi Di, Benjamin E. Turk, Yansheng Liu, Mandar Deepak Muzumdar

The paper examines the molecular effects of seven KRAS mutant variants in pancreatic cancer cells and finds that baseline cellular state, not allele identity, primarily drives molecular variation.

bioRxiv · Mar 12, 2026 · PreprintCancer Biology

Data-independent Acquisition-based Proteome and Phosphoproteome Profiling across Six Melanoma Cell Lines Reveals Determinants of Proteotypes

Erli Gao, Wenxue Li, Chongde Wu, Wenguang Shao, Yi Di, Yansheng Liu

This study uses DIA-MS to profile proteomes and phosphoproteomes of melanoma cell lines, revealing proteotype determinants and validating DIA-MS as a competitive method.

Molecular Omics · Feb 16, 2021Peer-reviewedSystems Biology

BoxCarmax: a high-selectivity data-independent acquisition mass spectrometry method for the analysis of protein turnover and complex samples

Barbora Šalovská, Wenxue Li, Yi Di, Yansheng Liu

BoxCarmax improves DIA-MS analysis of protein turnover and complex samples by enhancing quantitative accuracy in SILAC and pSILAC experiments.

Analytical Chemistry · Feb 3, 2021Peer-reviewedSystems Biology

Global impact of phosphorylation on protein endurance

Chongde Wu, Qian Ba, Wenxue Li, Barbora Šalovská, Pingfu Hou, Torsten Mueller, George Rosenberger, Erli Gao, Yi Di, Yansheng Liu

The paper introduces DeltaSILAC, a proteomic method to quantify how phosphorylation affects protein endurance in cancer cells, revealing its global impact on protein turnover and identifying sequence features associated with endurance changes.

bioRxiv · Mar 12, 2020 · PreprintSystems Biology