Author

Cassandra Santaella Bishop

Yale UniversityORCID 0000-0001-9153-9615Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Mandar Deepak MuzumdariD· 2 shared Yansheng LiuiD· 2 shared Barbora ŠalovskáiD· 1 shared Benjamin E. TurkiD· 1 shared Christian Felipe RuiziD· 1 shared Jaffarguriqbal SinghiD· 1 shared Moitrayee BhattacharyyaiD· 1 shared Wenxue LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Mandar Deepak MuzumdarORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 12, 2026

Baseline cellular state dictates the molecular impact of KRAS mutant variants in pancreatic cancer cells

Yanixa Quiñones-Avilés, Barbora Šalovská, Cassandra Santaella Bishop…·Mandar Deepak Muzumdar

The paper examines the molecular effects of seven KRAS mutant variants in pancreatic cancer cells and finds that baseline cellular state, not allele identity, primarily drives molecular variation.

DOI 10.64898/2026.03.10.710185

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJun 20, 2025

Phosphoinositide 3-kinase regulates wild-type RAS signaling to confer resistance to KRAS inhibition

Xiangyu Ge, Jaffarguriqbal Singh, Wenxue Li…·Mandar Deepak Muzumdar

This study shows PI3K promotes resistance to KRAS inhibition in PDAC by activating wild-type RAS signaling through GAB1 recruitment and MAPK activation.

1 citation

humanproteomics

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