Author

John C Price

Brigham Young UniversityORCID 0000-0002-6780-5247Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

John C. Price1 paper · Brigham Young University

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Ariel E. A. Denos· 2 shared Jared M. Elison· 2 shared Noah E. EarlsiD· 2 shared Noah G. MoraniD· 2 shared Benjamin Jones· 1 shared Benjamin S. JonesiD· 1 shared Chad D. HyeriD· 1 shared Christian Garrard· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Ariel E. A. Denos

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2 papers

Recent·Most cited

Ontological Analysis of Brain Proteostasis Highlights the Sex-Dependent Trajectory of ApoE Isoform-Specific Regulation

Ariel E. A. Denos, Benjamin Jones, Noah G. Moran, Ethan Smith, Katie Brown, Noah E. Earls, Rebecca Burlette, Christian Garrard, ELISE CLARK, Esteban Coleman, Jared M. Elison, Jason Wells, Jossue Matute, Joshua Brown, Martin Sorensen, , John C Price

The paper uses proteomic analysis in ApoE knock-in mice to show sex-dependent differences in proteostasis regulation by ApoE isoforms, with ApoE4 showing early metabolic and mitochondrial changes.

bioRxiv · Jun 30, 2026 · PreprintBiochemistry

Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain

Nathan R. Zuniga, Noah E. Earls, Ariel E. A. Denos, Jared M. Elison, Benjamin S. Jones, Ethan G. Smith, Noah G. Moran, Katie L. Broce, Gerome M. Romero, Chad D. Hyer, Kimberly B. Wagstaff, Haifa M. Almughamsi, Mark K. Transtrum, John C. Price

This study uses quantitative and kinetic proteomics to show that ApoE isoforms 2 and 4 alter mitochondrial protein regulation in the mouse brain compared to ApoE3, with distinct impacts on proteostasis.

PLoS Computational Biology · Dec 12, 2024Peer-reviewedBiochemistry