Molecular BiologybioRxivPreprint
Incongruent end structures of leading and lagging telomeres dictate the nature of end replication problem
Tiantian Ye, Qingqing Yuan, Shuheng Wu…·Jin‐Qiu Zhou
The paper investigates telomere end replication in yeast, showing that lagging strand telomeres have a 3' overhang while leading strand telomeres are blunt, with RNase H2 removing the last RNA primer.
DOI 10.1101/2025.02.23.639772