Jin‐Qiu Zhou

The paper introduces a CRISPR/Cas9 system in S. pombe to study telomere replication, revealing RNase H2-dependent RNA primer removal in lagging-strand telomeres.

The paper investigates telomere end replication in yeast, showing that lagging strand telomeres have a 3' overhang while leading strand telomeres are blunt, with RNase H2 removing the last RNA primer.

This study shows that deleting subtelomeric X- and Y-elements in yeast does not affect telomere length or silencing, but impacts telomere maintenance when telomerase is inactivated.

This study fuses chromosomes 15 and 17 in mouse haploid embryonic stem cells and finds minimal impact on gene expression, pluripotency, and mouse development.