Tiantian Ye

The paper introduces a CRISPR/Cas9 system in S. pombe to study telomere replication, revealing RNase H2-dependent RNA primer removal in lagging-strand telomeres.

The paper investigates how cohesin acetylation and ATPase activity regulate chromatin loop formation and cohesion in yeast, showing they operate through distinct mechanisms.

The paper investigates telomere end replication in yeast, showing that lagging strand telomeres have a 3' overhang while leading strand telomeres are blunt, with RNase H2 removing the last RNA primer.

ASHIC improves diploid Hi-C analysis by modeling allele-specific chromatin structures, outperforming existing methods in low coverage and low SNP density scenarios.