Martin E. van Royen

This study compares EV yield from HEK293 cells in shaker flasks and bioreactors, finding a 3-fold increase in EV yield with bioreactors.

This paper shows HBx promotes hepatocyte survival and reduces differentiation in human liver organoids, potentially contributing to liver cancer.

The paper identifies CHEK1 and BIRC5 as therapeutic targets in ARID1A-deficient bladder cancer using patient-derived tumoroids and public datasets.

This study investigates the role of LRP10 in Lewy body diseases, showing it regulates α-synuclein levels and interacts with a disease-associated variant.

This study develops a mouse model to monitor Mecp2 reactivation in neural stem cells and identifies genetic and epigenetic factors influencing reactivation of the inactive X chromosome.