Author

Natasja F. J. Dits

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1

Frequent Co-Authors

Martin E. van RoyeniD· 2 shared Ana Carreras MascaroiD· 1 shared Andrew StubbsiD· 1 shared Anne S. Bolijn· 1 shared Bart J. JansseniD· 1 shared Chris H. BangmaiD· 1 shared Christian R. RauschiD· 1 shared Cristina Bernal· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioengineering

Martin E. van RoyenORCID

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3 papers

Recent·Most cited

Small-scale bioreactor cultivation of HEK293-based suspension cells increases extracellular vesicle yield

Wouter W. Woud, Emerson Bryan Dilla, Natasja F. J. Dits, T. Keijzer, Cristina Bernal, Martin E. van Royen, Elena S. Martens‐Uzunova, Jeroen de Vrij

This study compares EV yield from HEK293 cells in shaker flasks and bioreactors, finding a 3-fold increase in EV yield with bioreactors.

bioRxiv · Jul 24, 2026 · PreprintBioengineering

LRP10 as a novel α-synuclein regulator in Lewy body diseases

Ana Carreras Mascaro, Martyna M. Grochowska, Valerie Boumeester, Natasja F. J. Dits, Ece Naz Bilgiҫ, Guido J. Breedveld, Leonie J.M. Vergouw, Frank Jan de Jong, Martin E. van Royen, Vincenzo Bonifati, Wim J. Mandemakers

This study investigates the role of LRP10 in Lewy body diseases, showing it regulates α-synuclein levels and interacts with a disease-associated variant.

bioRxiv · May 12, 2023 · PreprintNeuroscience

Detection of fusion transcripts and their genomic breakpoints from RNA sequencing data

Youri Hoogstrate, Malgorzata A. Komor, René Böttcher, Job van Riet, Harmen J.G. van de Werken, Stef van Lieshout, Ralf Hoffmann, Evert van den Broek, Anne S. Bolijn, Natasja F. J. Dits, Daoud Sie, David van der Meer, Floor Pepers, Chris H. Bangma, Geert J.L.H. van Leenders, , Guido W Jenster

Dr. Disco identifies fusion transcripts and genomic breakpoints using non poly(A)-enriched RNA-seq data, revealing transcribed rearrangements and their expression effects in cancer samples.

bioRxiv · May 17, 2021 · PreprintBioinformatics