Author

Sabine Spijker

Amsterdam NeuroscienceORCID 0000-0002-6814-2019Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

August Benjamin SmitiD· 3 shared Danai RigaiD· 1 shared Demirhan Çetereisi· 1 shared Femke Roig KuhniD· 1 shared Frank KoopmansiD· 1 shared Huibert D. MansvelderiD· 1 shared Ioannis KramvisiD· 1 shared Ka Wan LiiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

August Benjamin SmitORCID

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3 papers

Recent·Most cited

NeuroscienceCellsPeer-reviewedApr 21, 2026

A Tiered Approach to Human Synapse Proteomics: Optimized LC-MS/MS Analysis of Whole-Tissue and Synaptosome Preparations from Frozen Post-Mortem Brain Samples

Femke Roig Kuhn, Remco V. Klaassen, Frank Koopmans…·Sabine Spijker

The paper compares whole-tissue and synaptosome proteomics using LC-MS/MS to evaluate synaptic protein detection, recommending a tiered approach for studying brain disorders.

DOI 10.3390/cells15080736

humanproteomics

𝕏 PostBluesky

NeuroscienceScientific ReportsPeer-reviewedOct 14, 2020

From stress to depression: Development of extracellular matrix-dependent cognitive impairment following social stress

Maija-Kreetta Koskinen, Yvar van Mourik, August Benjamin Smit…·Sabine Spijker

This study investigates how social stress leads to cognitive impairment and affective disturbances in rats, revealing distinct phases of hippocampal extracellular matrix remodeling associated with different aspects of depression.

61 citationstop 3%

ratstatistical model

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NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewedOct 25, 2019

Gpr158 deficiency impacts hippocampal CA1 neuronal excitability, dendritic architecture, and affects spatial learning

Demirhan Çetereisi, Ioannis Kramvis, Titia Gebuis…·Sabine Spijker

This study shows that Gpr158 deficiency in mice leads to impaired spatial memory and altered CA1 neuronal excitability and dendritic structure.

31 citations

mouseelectronic health records

𝕏 PostBluesky