Bruce A. Rosa

The paper generates a single-cell transcriptome atlas of adult male and female human hookworms, identifying sex-specific cell types and molecular markers to uncover new biological insights and potential therapeutic targets.

This study shows ETEC heat-labile toxin stabilizes β-catenin and alters intestinal epithelial differentiation, leading to impaired nutrient absorption and growth issues.

The paper identifies proteins dysregulated in pleomorphic neoplasms of Onchocerca volvulus using mass spectrometry and laser capture microdissection, showing systemic protein expression changes associated with tumor development and worm mortality.

The paper identifies extrasynaptic volume transmission as a non-synaptic signaling route in nematodes, showing that neuropeptides in pseudocoelomic fluid modulate reproductive function and behavior.

This paper compares genomes of 81 nematode and platyhelminth species to identify gene families related to parasitism and prioritize new drug targets.