Author
Washington University in St. LouisORCID 0009-0001-0208-4143Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Alaullah Sheikh, Bipul Setu, Nikhilesh Joardar…·James M. Fleckenstein
This study shows ETEC heat-labile toxin stabilizes β-catenin and alters intestinal epithelial differentiation, leading to impaired nutrient absorption and growth issues.
Tim J. Vickers, David P. Buckley, Nazia Khatoon…·James M. Fleckenstein
This study shows that parenteral vaccination with recombinant EtpA glycoprotein can protect against ETEC intestinal colonization in mice, with protection dependent on vaccination schedule and adjuvant type.
Alaullah Sheikh, Debayan Ganguli, Tim J. Vickers…·James M. Fleckenstein
The paper shows that host-derived CEACAM-laden vesicles capture ETEC and its toxins, reducing pathogen load and neutralizing toxins during infection.
Bipul Setu, Qian Nie, Grace Echele, Susan A. Spencer
This study identifies CAPS as a microtubule-binding protein essential for spindle formation and mitosis, with potential implications for cancer biology.