Author

John C Martin

Washington University in St. LouisORCID 0000-0003-1235-5952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Bruce A. RosaiD· 3 shared Makedonka MitrevaiD· 3 shared Adam James ReidiD· 1 shared Aidan Mark EmeryiD· 1 shared Alan TraceyiD· 1 shared Alaullah SheikhiD· 1 shared Andrew R. LeachiD· 1 shared Antonio MuroiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioinformatics

Bruce A. RosaORCID

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3 papers

Recent·Most cited

BioinformaticsiSciencePeer-reviewedOct 25, 2025

A single-cell transcriptome atlas of adult male and female human hookworm Ancylostoma ceylanicum

Suman Bharti, Bruce A. Rosa, John C Martin, Makedonka Mitreva

The paper generates a single-cell transcriptome atlas of adult male and female human hookworms, identifying sex-specific cell types and molecular markers to uncover new biological insights and potential therapeutic targets.

4 citations

humanscRNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintOct 2, 2025

ETEC heat-labile toxin promotes β-catenin stabilization and transcriptional reprogramming to disrupt intestinal epithelial differentiation

Alaullah Sheikh, Bipul Setu, Nikhilesh Joardar…·James M. Fleckenstein

This study shows ETEC heat-labile toxin stabilizes β-catenin and alters intestinal epithelial differentiation, leading to impaired nutrient absorption and growth issues.

DOI 10.1101/2025.10.02.680135

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsNature GeneticsPeer-reviewedOct 29, 2018

Comparative genomics of the major parasitic worms

Avril Coghlan, James Anthony Cotton, Nancy E. Holroyd…·Lian-Chen Wang

This paper compares genomes of 81 nematode and platyhelminth species to identify gene families related to parasitism and prioritize new drug targets.

562 citationstop 1%

whole-genome sequencingstatistical model

𝕏 PostBluesky