Cancer BiologyDNA repairPeer-reviewed
DNA polymerase beta expression in head & neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint
Md Maruf Khan, Wynand Paul Roos, Charlotte R. Pearson…·Robert William Sobol
This study shows that DNA polymerase beta modulates the PARG-mediated replication checkpoint in HNSCC, and combining PARG and ATR/CHK1 inhibitors overcomes resistance.
7 citations