Bethany Signal

The paper introduces a Python library to quickly determine the strandedness of paired-end RNA-Seq data, improving the accuracy of downstream analyses.

Borf improves ORF prediction in de-novo transcriptomes by addressing strand specificity and start site selection, reducing false positives and improving accuracy.

This study investigates gene expression dynamics in mouse embryonic stem cells at high temporal resolution, revealing new insights into transcriptional regulation and noncoding RNA roles.

The paper develops a machine-learning algorithm to annotate human splicing branchpoints from genome sequence, identifying 85% of annotated introns and confirming deleterious mutations.