Author

Andrew Charles Perkins

Monash UniversityORCID 0000-0003-3644-7093Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Bethany SignaliD· 1 shared Brian GlossiD· 1 shared Caroline McNamara· 1 shared Christine R. KeenaniD· 1 shared David M. RossiD· 1 shared Dominik C. KaczorowskiiD· 1 shared Franziska GruhliD· 1 shared Gerlinda M. Amor· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperSystems Biology

Bethany SignalORCID

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3 papers

Recent·Most cited

Cancer BiologyBlood AdvancesPeer-reviewedMay 8, 2026

Single cell long-read genotyping of transcriptomes reveals discrete mechanisms of clonal evolution in post-myeloproliferative neoplasm acute myeloid leukemia.

Julian Grabek, Jasmin Straube, Leanne T. Cooper…·Steven Lane

This study uses a new long-read sequencing method to genotype mutations in single cells from MPN patients, revealing how mutations drive disease progression to AML.

4 citationstop 2%

humanscRNA-seq

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Synthetic BiologyNature CommunicationsPeer-reviewedSep 23, 2022

Activation of stably silenced genes by recruitment of a synthetic de-methylating module

Wing Fuk Chan, Hannah D. Coughlan, Yunshun Chen…·Rhys S. Allan

This study develops a synthetic de-methylating module to reactivate stably silenced genes by combining TET1's demethylating activity with transcriptional activators.

26 citations

DNA methylationexperimental assay

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Systems BiologyScientific ReportsPeer-reviewedJul 21, 2017

High temporal resolution of gene expression dynamics in developing mouse embryonic stem cells

Brian Gloss, Bethany Signal, Seth W. Cheetham…·Marcel E. Dinger

This study investigates gene expression dynamics in mouse embryonic stem cells at high temporal resolution, revealing new insights into transcriptional regulation and noncoding RNA roles.

14 citations

mousebulk RNA-seq

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