BiochemistryeLifePeer-reviewed
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
Rohan Eapen, Cynthia N. Okoye, Christopher J. Stubbs…·Laura S. Itzhaki
This study develops D-box peptides that inhibit APC/C by binding Cdc20, showing they are more potent than Apcin and can drive protein degradation.
DOI 10.7554/elife.104238.3