Author

Catherine Lindon

University of CambridgeORCID 0000-0003-3554-2574Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Catherine Lindon1 paper

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Annabel Cardno· 1 shared Christopher J. StubbsiD· 1 shared Christopher Phillips· 1 shared Cynthia N. OkoyeiD· 1 shared David BarfordiD· 1 shared David R. SpringiD· 1 shared Deniz RadiD· 1 shared Eileen J. Fisher· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

Annabel Cardno

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3 papers

Recent·Most cited

BiochemistryeLifePeer-reviewedSep 1, 2025

Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome

Rohan Eapen, Cynthia N. Okoye, Christopher J. Stubbs…·Laura S. Itzhaki

This study develops D-box peptides that inhibit APC/C by binding Cdc20, showing they are more potent than Apcin and can drive protein degradation.

DOI 10.7554/elife.104238.3

experimental assaydrug response / drug discovery

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Cell BiologybioRxivPreprintApr 23, 2025

Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

Annabel Cardno, Karen Roberts, Catherine Lindon

This study identifies deubiquitinases UCHL5 and OTUD6A that modulate AURKA degradation by PROTACs, revealing target-specific and ligase-dependent mechanisms.

DOI 10.1101/2025.04.23.650020

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyPLoS ONEPeer-reviewedNov 11, 2024

Post-transcriptional control drives Aurora kinase A expression in human cancers

Roberta Cacioppo, Deniz Rad, Giulia Pagani…·Catherine Lindon

This study identifies post-transcriptional mechanisms, including APA and miRNA regulation, that influence AURKA expression in cancer.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky