Author

Fangzhou He

Xi'an Jiaotong UniversityORCID 0000-0002-6853-6544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jin Zhang· 2 shared John Y.-J. ShyyiD· 2 shared Wenyang Hao· 2 shared Ying XiongiD· 2 shared Yuyang Lei· 2 shared Zuyi YuaniD· 2 shared Baoyu Li· 1 shared Chen WangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMolecular Biology

Jin Zhang

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2 papers

Recent·Most cited

Obesity Increases Atherosclerosis Susceptibility via Inter-tissue miR-30e-SLC7A11 Axis

Chen Wang, Jianqing She, Xiaoli Qian, Haoyu Wu, Wenyang Hao, Xiao Liang, Ning Guo, Xulei Dai, Fangzhou He, Sisi He, Jin Zhang, Yuyang Lei, Xiaozhen Zhuo, Hongbing Li, Yongbai Luo, , Zuyi Yuan

This study shows that obesity increases atherosclerosis through an inter-tissue miR-30e-SLC7A11 axis, where adipose-derived miR-30e-5p targets SLC7A11 in vascular endothelial cells, leading to metabolic and functional impairments.

Circulation Research · Sep 11, 2026Peer-reviewedMolecular Biology

ACE2 Phosphorylation Modulates Angiogenesis via the Activator Protein-1

Yuyang Lei, Yuanming Xing, Yi Lei, Qiangyun Liu, Tong-You Wade Wei, Baoyu Li, Fangzhou He, Ziru Wu, Lu Wang, Lu Wang, Wenyang Hao, Jin Zhang, Ying Xiong, Juan Zhou, Xiaohong Wang, , Zuyi Yuan

This study shows that ACE2 phosphorylation at Ser-680 modulates angiogenesis by affecting AP-1 activation in vascular endothelial cells.

bioRxiv · Oct 17, 2025 · PreprintCell Biology