Author

Yuyang Lei

First Affiliated Hospital of Xi'an Jiaotong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

John Y.-J. ShyyiD· 3 shared Zuyi YuaniD· 3 shared Fangzhou HeiD· 2 shared Haoyu WuiD· 2 shared Jin Zhang· 2 shared Juan ZhouiD· 2 shared Wenyang Hao· 2 shared Ying XiongiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMolecular Biology

John Y.-J. ShyyORCID

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Author profile →

3 papers

Recent·Most cited

Obesity Increases Atherosclerosis Susceptibility via Inter-tissue miR-30e-SLC7A11 Axis

Chen Wang, Jianqing She, Xiaoli Qian, Haoyu Wu, Wenyang Hao, Xiao Liang, Ning Guo, Xulei Dai, Fangzhou He, Sisi He, Jin Zhang, Yuyang Lei, Xiaozhen Zhuo, Hongbing Li, Yongbai Luo, , Zuyi Yuan

This study shows that obesity increases atherosclerosis through an inter-tissue miR-30e-SLC7A11 axis, where adipose-derived miR-30e-5p targets SLC7A11 in vascular endothelial cells, leading to metabolic and functional impairments.

Circulation Research · Sep 11, 2026Peer-reviewedMolecular Biology

ACE2 Phosphorylation Modulates Angiogenesis via the Activator Protein-1

Yuyang Lei, Yuanming Xing, Yi Lei, Qiangyun Liu, Tong-You Wade Wei, Baoyu Li, Fangzhou He, Ziru Wu, Lu Wang, Lu Wang, Wenyang Hao, Jin Zhang, Ying Xiong, Juan Zhou, Xiaohong Wang, , Zuyi Yuan

This study shows that ACE2 phosphorylation at Ser-680 modulates angiogenesis by affecting AP-1 activation in vascular endothelial cells.

bioRxiv · Oct 17, 2025 · PreprintCell Biology

Chronic kidney disease exacerbates hyperlipidemia and atherosclerosis via miR-148a-3p targeting SIK1/AMPKα1 in liver

Yuzhi Huang, Ting Li, Erwei Hu, Peiyao Zhang, Xueying Feng, Heze Fan, Zihao Wang, Yuyang Lei, Chen Wang, Wenbo Yang, Lijun Wang, Peining Liu, Bin Du, Yan Wu, Wenbo Li, , Juan Zhou

This study identifies miR-148a-3p as a key mediator of CKD-induced hyperlipidemia and atherosclerosis by targeting SIK1/AMPK1 in the liver via exosomal transfer.

bioRxiv · Oct 8, 2025 · PreprintPathology