Author

Yi Lei

First Affiliated Hospital of Xi'an Jiaotong UniversityORCID 0000-0001-9596-3472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Xiaohong WangiD· 2 shared Baoyu Li· 1 shared Fangzhou HeiD· 1 shared Jiayu LiuiD· 1 shared Jie ZhouiD· 1 shared Jin Zhang· 1 shared John Y.-J. ShyyiD· 1 shared Juan ZhouiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Xiaohong WangORCID

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2 papers

Recent·Most cited

Kindlin-2-Moesin interaction orchestrates sprouting angiogenesis via modulating endothelial membrane mechanics and VEGF signaling

Lu Wang, Yuxin Fu, Zeyang Yu, Yi Lei, Tianjing Yang, Jiayu Liu, Nina Ma, Yuming Liu, Kunfu Ouyang, Kai Zhang, Junhao Hu, Xi Fang, Ying Shen, Jie Zhou, Xiaohong Wang

This study identifies Kindlin-2-Moesin interaction as a regulator of sprouting angiogenesis by modulating endothelial membrane tension and VEGF signaling.

bioRxiv · Feb 26, 2026 · PreprintDevelopmental Biology

ACE2 Phosphorylation Modulates Angiogenesis via the Activator Protein-1

Yuyang Lei, Yuanming Xing, Yi Lei, Qiangyun Liu, Tong-You Wade Wei, Baoyu Li, Fangzhou He, Ziru Wu, Lu Wang, Lu Wang, Wenyang Hao, Jin Zhang, Ying Xiong, Juan Zhou, Xiaohong Wang, , Zuyi Yuan

This study shows that ACE2 phosphorylation at Ser-680 modulates angiogenesis by affecting AP-1 activation in vascular endothelial cells.

bioRxiv · Oct 17, 2025 · PreprintCell Biology