Author

Gail A. Hecht

Loyola University ChicagoORCID 0000-0002-6877-8463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Amanda BirminghamiD· 1 shared Angelo Morales· 1 shared Antonio Gonzalez· 1 shared Caitriona BrennaniD· 1 shared Daniel McDonald· 1 shared Dilara M. Sevilir· 1 shared Gail L. AckermanniD· 1 shared Gillian M. Wright· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Amanda BirminghamORCID

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2 papers

Recent·Most cited

Genome-resolved ecology and evolution of the microbiome enabled by quantitative long-read metagenomics

M. Omar Din, Caitriona Brennan, Jianshu Zhao, Renee E. Oles, Lucas Patel, Amanda Birmingham, Dilara M. Sevilir, Lauren Hansen, Gillian M. Wright, Madison Ambre, Meika Tomita, Tara Boyer, Antonio Gonzalez, Gail L. Ackermann, Daniel McDonald, , Rob D. Knight

This paper introduces LRQ, a long-read metagenomics method that enables absolute strain abundance measurement and resolves microbial evolution in a Crohn's disease patient over eight years.

bioRxiv · Sep 29, 2026 · PreprintMicrobiology

Spef1 is a microvillar component that limits apical actomyosin contractility and preserves intestinal barrier function

Rocío Tapia, Angelo Morales, Gail A. Hecht, Matthew J. Tyska

This study identifies Spef1 as a microvillar component that regulates apical actomyosin contractility to maintain intestinal barrier function.

Current Biology · Jan 16, 2026Peer-reviewedCell Biology