Viktor Lemmens

This study develops a biosafety level 2-compatible panel of orthoebolaviruses for screening broad-spectrum antivirals, identifying both broad-acting and virus-specific candidates.

This study evaluates cross-protection of Ebola and Sudan vaccines against Bundibugyo virus using a surrogate challenge model in mice, finding partial protection and suggesting non-neutralizing mechanisms play a role.

This study develops a yellow fever 17D reporter virus expressing thymidine kinase to enable prodrug activation and bioorthogonal labeling of infected cells for tracking viral replication and tissue tropism.

This study shows 4'-fluorouridine inhibits Oropouche virus replication in vitro and in animal models, with no resistant variants observed.

This paper develops a single-dose YF17D-vectored SARS-CoV-2 vaccine candidate that induces neutralizing antibodies and protects against infection in hamsters.