Juliana Marulanda

Matrix Gla Protein deficiency reveals a previously unrecognized mucosal calcification in the mouse airways

This study identifies an early physiologic calcification process in mouse tracheal cartilage and reveals MGP deficiency causes additional mucosal calcification, explaining respiratory symptoms in Keutel syndrome.

Arterial Elastin Abundance, Rather Than Orthologue Origin, Modulates Medial Arterial Calcification in Matrix Gla Protein-Deficient Mice

The paper shows that arterial elastin abundance, not its origin, affects medial calcification in MGP-deficient mice, with reduced elastin delaying calcification and human elastin restoring it.