Pablo Augusto de Souza Fonseca

Divergent gene expression in alcohol and opioid usedisorders results in consistent alterations in functional networks in the Dorsolateral Prefrontal Cortex

This study identifies divergent gene expression in AUD and OUD but finds shared biological pathways in the dorsolateral prefrontal cortex, suggesting potential therapeutic targets.

NAToRA, a relatedness-pruning method to minimize the loss of dataset size in genetic and omics analyses

NATO RA prunes relatedness in genetic datasets to minimize data loss, outperforming existing methods by retaining more individuals while removing all relatives.