Maria Fernanda Lima‐Costa

Comparing the effect of imputation reference panel composition in four distinct Latin American cohorts

This study evaluates how imputation reference panel composition affects imputation quality in four Latin American cohorts, finding that increasing Latin American representation improves quality but results vary by population and chromosome.

X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson Disease

The paper conducts an X-chromosome association study in Latin American cohorts, identifying new loci linked to Parkinson Disease and replicating previous findings.

Whole-genome sequencing of 1,171 elderly admixed individuals from the largest Latin American metropolis (Sao Paulo, Brazil)

This study presents a high-coverage whole-genome sequencing dataset of 1,171 admixed elderly Brazilians, identifying novel variants and demonstrating the utility of WGS for genomic and clinical research in underrepresented populations.

NAToRA, a relatedness-pruning method to minimize the loss of dataset size in genetic and omics analyses

NATO RA prunes relatedness in genetic datasets to minimize data loss, outperforming existing methods by retaining more individuals while removing all relatives.

Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass- and fat mass-indexes

The paper identifies a West African-associated regulatory variant with a strong female-specific effect on BMI and fat mass in Brazilian admixed populations.

Origins, admixture dynamics and homogenization of the African gene pool in the Americas

The paper analyzes African genetic contributions to the Americas, showing regional ancestry patterns and admixture dynamics linked to historical factors.

The genomic impact of European colonization of the Americas

This study analyzes the genetic impact of European colonization on the Americas using genome-wide data from 12,000 individuals, revealing complex contributions from European, African, and other sources.

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

This study identifies 210 genetic loci associated with the PR interval through multi-ancestry GWAS, highlighting their role in cardiac conduction and cardiovascular disease.