Author

Steve Lefever

Ghent UniversityORCID 0000-0002-6936-8239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 2

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Jo VandesompeleiD· 4 shared Justine NuytensiD· 3 shared Pieter MestdaghiD· 3 shared Pieter‐Jan VoldersiD· 3 shared Francisco Avila CobosiD· 2 shared Gary P. SchrothiD· 2 shared Jan KösteriD· 2 shared Jasper AnckaertiD· 2 shared

Activity by Year

2018-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Jo VandesompeleORCID

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4 papers

Recent·Most cited

Performance evaluation of three DNA sample tracking tools in a whole exome sequencing workflow

Gertjan Wils, Céline Helsmoortel, Pieter‐Jan Volders, Inge Vereecke, Mauro Milazzo, Jo Vandesompele, Frauke Coppieters, Kim De Leeneer, Steve Lefever

The paper evaluates three DNA sample tracking tools in a whole exome sequencing workflow, finding the pxlence kit most reliable and cost-effective.

Molecular Diagnosis & Therapy · May 28, 2022Peer-reviewedGenomics

Charting extracellular transcriptomes in The Human Biofluid RNA Atlas

Eva Hulstaert, Annelien Morlion, Francisco Avila Cobos, Kimberly Verniers, Justine Nuytens, Eveline Vanden Eynde, Nurten Yigit, Jasper Anckaert, Anja M. Geerts, Pieter Hindryckx, Peggy Jacques, Guy Brusselle, Ken R. Bracke, Tania Maes, Thomas L.A. Malfait, , Pieter Mestdagh

The paper creates a comprehensive atlas of RNA transcriptomes across 20 human biofluids, revealing significant differences in RNA concentration and composition, and validates potential biomarkers in disease cohorts.

Cell Reports · Dec 1, 2020Peer-reviewedGenomics

The RNA Atlas, a single nucleotide resolution map of the human transcriptome

Lucía Lorenzi, Hua‐Sheng Chiu, Francisco Avila Cobos, Stephen Gross, Pieter‐Jan Volders, Robrecht Cannoodt, Justine Nuytens, Katrien Vanderheyden, Jasper Anckaert, Steve Lefever, Tine Goovaerts, Thomas B. Hansen, Scott Kuersten, Nele Nijs, Tom Taghon, , Pieter Mestdagh

The paper presents a comprehensive human transcriptome atlas with single-nucleotide resolution, identifying thousands of novel RNA species and regulatory interactions.

bioRxiv · Oct 17, 2019 · PreprintGenetics

Targeted genomic screen reveals focal long non-coding RNA copy number alterations in cancer

Pieter‐Jan Volders, Jo Vandesompele, Steve Lefever, Shalina Baute, Justine Nuytens, Katrien Vanderheyden, Björn Menten, Pieter Mestdagh

The paper identifies focal copy number alterations in lncRNAs across cancer cell lines, suggesting potential oncogenic or tumor suppressive roles.

Non-Coding RNA · Sep 13, 2018Peer-reviewedGenetics