Derek S. Sarovich

Using population-level whole-genome sequencing to profile colistin resistance evolution dynamics in diverse clinical Pseudomonas aeruginosa lineages

The paper uses population-level whole-genome sequencing to study colistin resistance evolution in diverse Pseudomonas aeruginosa lineages under increasing colistin pressure.

Prevalence of Pseudomonas aeruginosa in Australian wild birds, native wildlife, livestock and domestic animals

This study screens DNA samples from Australian wildlife and domestic animals for Pseudomonas aeruginosa prevalence and resistance genotypes, finding lower rates than international studies.

A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry

This study shows that L-type pyocins inhibit the BAM complex at the cell surface to kill Pseudomonas aeruginosa without entering the cell.

Comparative genomics of Nocardia seriolae reveals recent importation and subsequent widespread dissemination in mariculture farms in South Central Coast, Vietnam

The paper analyzes Nocardia seriolae strains from Vietnam and Taiwan to trace their origin and spread, finding a single clade with limited genetic diversity and suggesting widespread transmission among mariculture farms.

Taking the next-gen step: comprehensive antimicrobial resistance detection from Burkholderia pseudomallei

This study develops ARDaP, a tool for comprehensive antimicrobial resistance detection in Burkholderia pseudomallei, outperforming existing tools by identifying SNPs, indels, CNVs, and gene loss determinants, including previously undescribed ones.

Tracing the environmental footprint of the Burkholderia pseudomallei lipopolysaccharide genotypes in the tropical \"Top End\" of the Northern Territory, Australia

This study uses whole-genome sequencing and geographical mapping to show that lipopolysaccharide (LPS) types in Burkholderia pseudomallei correlate with specific regions in the Northern Territory, Australia, and can serve as geographical markers.

Evolution and global transmission of a multidrug-resistant, community-associated MRSA lineage from the Indian subcontinent

This study traces the origin and global spread of a multidrug-resistant MRSA lineage from the Indian subcontinent, showing its emergence through plasmid acquisition and intercontinental transmission.