Alexis D. Franklin

Cooperative thalamocortical circuit mechanism for sensory prediction errors

The paper identifies a thalamocortical disinhibitory circuit in mouse V1 that selectively amplifies unexpected visual stimuli, implementing sensory prediction errors through VIP and SOM interneuron interactions.

Epigenomic Diversity of Cortical Projection Neurons in the Mouse Brain

The paper links epigenomic properties of cortical projection neurons to their anatomical and projection patterns using single-nucleus DNA methylation sequencing in mice.

Distinct 'driving' versus 'modulatory' influences of different visual corticothalamic pathways

The paper shows that layer 5 corticothalamic projections drive visual responses in the pulvinar, while layer 6 provides baseline excitation, with subcortical inputs also contributing.

Context-Dependent and Dynamic Functional Influence of Corticothalamic Pathways to First- and Higher-order Visual Thalamus

This study investigates how corticothalamic pathways modulate first- and higher-order visual thalamic nuclei in awake mice through optogenetic stimulation and electrophysiology, revealing context-dependent and dynamic effects.