Detection of histone modifications and full-length transcriptome in single cells identifies sequential epigenetic perceptiveness to lineage commitment
Marloes Blotenburg, Vivek Bhardwaj, Buys de Barbanson…·Alexander van Oudenaarden
The paper develops T-ChIC to detect histone modifications and full-length transcripts in single cells, revealing sequential epigenetic changes during lineage commitment in gastruloids.