Peter J. Zeller

The paper uses single-cell multimodal data to show how chromatin states and gene expression interact during early zebrafish development, revealing lineage-specific transcription factor regulation.

The paper introduces Dam&ChIC, a method for time-resolved chromatin profiling in single cells, revealing that genome-lamina detachment precedes H3K27me3 accumulation during X-chromosome inactivation.

This study shows that optimizing mouse embryonic stem cell pluripotency state improves the consistency and complexity of gastruloid development.

The paper develops T-ChIC to detect histone modifications and full-length transcripts in single cells, revealing sequential epigenetic changes during lineage commitment in gastruloids.

This study develops an engineered uterus-like microenvironment to study mouse embryo implantation, revealing coordination between trophoblast migration and embryo growth.

The paper introduces scChIX, a method to map multiple histone modifications in single cells by combining experimental and computational approaches, revealing chromatin state transitions in immune cells.

The paper develops sortChIC to map histone modifications in mouse hematopoietic cells, revealing hierarchical chromatin regulation during blood formation.