Author

Matthew S. Huver

Western UniversityORCID 0009-0001-8687-7115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Danielle E. JohnstoniD· 3 shared Silvia PeñuelaiD· 3 shared Brooke L. O’DonnelliD· 2 shared John Andrew RonaldiD· 2 shared John Joseph KellyiD· 2 shared Stephanie E. LeightoniD· 2 shared Andrew M. DeweyertiD· 1 shared Brant E. IsaksoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCancer Biology

Danielle E. JohnstonORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 9, 2026

Pannexin 1 Ablation Disrupts Cell Cycle Progression and Compromises the Structure of Melanoma Tumours

Stephanie E. Leighton, Danielle E. Johnston, Kevin Barr…·Silvia Peñuela

This study shows that PANX1 ablation disrupts cell cycle progression and tumor structure in melanoma, suggesting it as a therapeutic target.

DOI 10.64898/2026.10.08.757604

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 7, 2026

Pannexin 1 inhibition reduces tumorigenic properties of patient-derived glioblastoma cells through the HIPPO and Wnt signalling pathways

Danielle E. Johnston, Matthew S. Huver, Rehanna Kanji…·Silvia Peñuela

DOI 10.64898/2026.09.03.749222

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologyFEBS JournalPeer-reviewedJan 9, 2025

Pannexin 1 crosstalk with the Hippo pathway in malignant melanoma

Samar Sayedyahossein, Kenneth Huang, Christopher Zhang…·Silvia Peñuela

This study investigates the interaction between PANX1 and the Hippo pathway in melanoma, showing PANX1 modulates YAP levels and identifies potential therapeutic targets.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky