Author

Nona Struyf

Science for Life LaboratoryORCID 0000-0002-6975-0753Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Tom ErkersiD· 3 shared Albin ÖsterroosiD· 2 shared Olli KallioniemiiD· 2 shared Sofia Bengtzén· 2 shared Sören LehmanniD· 2 shared Akifumi Takaori‐KondoiD· 1 shared Akinori YodaiD· 1 shared Anna Bohlin· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCancer Biology

Tom ErkersORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Transcriptionally defined AML cell states associate with treatment response and microenvironmental remodeling

Nona Struyf, Leonard Hartmanis, Lucia Rico Pizarro, Albin Österroos, Anna Bohlin, Sofia Bengtzén, Sören Lehmann, Olli Kallioniemi, Tom Erkers

This study defines AML cell states through single-cell transcriptomics and links them to drug response and microenvironmental interactions, identifying state-specific vulnerabilities and resistance mechanisms.

bioRxiv · Jul 1, 2026 · PreprintCancer Biology

Chromatin landscape and epigenetic heterogeneity of acute myeloid leukemia

Yotaro Ochi, Markus Liew-Littorin, Yasuhito Nannya, Sofia Bengtzén, Bénédicte Piauger, Stefan Deneberg, Martin Jädersten, Vladimir Lazarević, Jörg Cammenga, Anna Robelius, Lovisa Wennström, Emma Ölander, Senji Kasahara, Nobuhiro Hiramoto, Nobuhiro Kanemura, , Seishi Ogawa

This study identifies 16 AML subgroups based on chromatin accessibility profiles using ATAC-seq in 1,563 cases, revealing epigenetic heterogeneity and its clinical and therapeutic implications.

bioRxiv · May 24, 2026 · PreprintCancer Biology

Proteomic profiling reveals pleiotropic antimetabolite activity of triciribine in acute lymphoblastic leukemia

Xuekang Qi, Georgios Mermelekas, Ondřej Hodek, Luay Aswad, Quentin Glaziou, Isabelle Rose Leo, Nona Struyf, Ioannis Siavelis, Henri Colyn Bwanika, Owen F.J. Hovey, Martin Haraldsson, Annika I. Johansson, Tom Erkers, Katja Pokrovskaja Tamm, Janne Lehtiö, Rozbeh Jafari

This study identifies triciribine's pleiotropic antimetabolite effects in ALL by showing its ADK-dependent activity and impact on multiple cellular pathways.

bioRxiv · Mar 16, 2026 · PreprintCancer Biology