Rozbeh Jafari

This study identifies triciribine's pleiotropic antimetabolite effects in ALL by showing its ADK-dependent activity and impact on multiple cellular pathways.

This paper introduces DIPx, a model predicting drug synergy using pathway activation scores, showing better performance than existing methods on both known and novel drug combinations.

This study identifies novel SETD8 inhibitors and shows their toxicity correlates with ribosome biogenesis regulators, suggesting a biomarker for targeted cancer therapy.

This study identifies additional proteoform targets of ibrutinib using thermal proteome profiling, revealing off-target interactions linked to immunomodulation and cellular processes.