Author

Loïc Brot

InsermORCID 0000-0002-6977-4253Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:metagenomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Harry SokoliD· 3 shared Ilias TheodorouiD· 2 shared Luisa De SordiiD· 2 shared Marianne De PaepeiD· 2 shared Quentin Lamy-BesnieriD· 2 shared Alberto DanielliiD· 1 shared Antoine CulotiD· 1 shared Camille DanneiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

Harry SokolORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Faecalibacterium prausnitzii induces an anti-inflammatory response and a metabolic reprogramming in human monocytes

Camille Danne, Rodrigo de Oliveira Formiga, Laura Creusot, Florian Marquet, Delphine Sedda, Laura Hua, Pauline Ruffié, Hang‐Phuong Pham, Loïc Brot, Iria Alonso Salgueiro, Marie‐Laure Michel, Philippe Langella, Jérémie H. Lefèvre, Harry Sokol, Nathalie Rolhion

This study shows that Faecalibacterium prausnitzii induces IL-10 production and metabolic changes in human monocytes, with anti-inflammatory effects and mitochondrial dependence.

Gastroenterology · Jan 19, 2026Peer-reviewedImmunology

Differential translocation of bacteriophages across the intestinal barrier in health and Crohn's disease

Clara Douadi, Quentin Lamy-Besnier, Ilias Theodorou, Olivier Schiettekatte, Yanis Sbardella, Loïc Brot, Paolo Emidio Costantini, Roberto Saporetti, Alberto Danielli, Matteo Calvaresi, Marianne De Paepe, Harry Sokol, Diego Garcia-Weber, Véronique Carrière, Sophie Thenet, Luisa De Sordi

The paper investigates phage translocation across the intestinal barrier in health and Crohn's disease, finding increased phage presence in blood samples from CD patients.

Cell Reports · Dec 24, 2025Peer-reviewedCell Biology

The human blood harbors a phageome which differs in Crohn's disease

Quentin Lamy-Besnier, Ilias Theodorou, Maud Billaud, Hao Zhang, Loïc Brot, Antoine Culot, Guillaume Abriat, Harry Sokol, Marianne De Paepe, Marie‐Agnès Petit, Luisa De Sordi

The paper studies the blood virome in healthy individuals and Crohn's disease patients, finding distinct viral communities associated with the disease.

bioRxiv · Jun 4, 2024 · PreprintMicrobiology